Endocrine Abstracts

Introduction: Primary aldosteronism (PA) is the most frequent curable form of hypertension. Hypokalemia is a late symptom of PA. Consequently, PA often is not diagnosed for many years. Our aim was to identify clinical and laboratory parameters in a large cohort of PA patients obtained during their first assessment.Methods: 96 consecutive patients prospectively studied since 2008 at the German Conn’s Registry Center in Munich were eligible for this s...

Recent studies indicating that normokaliemic primary aldosteronism (PA) is a more frequent cause of hypertension than previously expected led to an increased interest in biochemical screening strategies. We investigated biochemical diagnostic strategies used in different academic centres for patients documented in the German National Conn’s Registry. Data from 7 centres in 5 cities have been entered into a database by trained personnel. For analysis, results from 522 pati...

Context: Primary aldosteronism (PHA) is the most common cause of secondary hypertension. Distinguishing unilateral (UAH) from bilateral (BAH) and other causes of PHA is one of the greatest challenges in the diagnostic process. Adrenal venous sampling (AVS) is widely considered to be the gold standard for subtype differentiation.Methods: Technical and diagnostic outcome of AVS was analysed retrospectively in 59 patients with PHA who underwent AVS at the U...